Simple, rapid, and sensitive technologies to detect nucleic acid modifications have important
applications in genetic analysis, clinical diagnosis, and molecular biology. Because genetic …

The tear film covers the anterior eye and the precise balance of its various constituting
components is critical for maintaining ocular health. The composition of the tear film amphiphilic …

A new fluorescent nanoparticle based on lipid-modified cationic poly(fluorenylene phenylene)
(PFPL) was prepared and characterized. The PFPL is amphiphilic and has two unique …

DNA cleavage by nucleases is essential to genetic information processing (eg, DNA replication,
recombination, repair),[1] and is also extensively utilized as a necessary tool in PCR …

As current diagnostic markers for dry eye syndrome (DES) are lacking in both sensitivity and
specificity, a pressing concern exists to develop activity markers that closely align with the …

MicroRNA (miRNA) analysis in a single cell is extremely important because it allows deep
understanding of the exact correlation between the miRNAs and cell functions. Herein, we …

Single nucleotide polymorphisms (SNPs) comprise the most abundant source of genetic
variation in the human genome. A SNP and allele frequency analysis method was established …

In this work we created electrospun fibrous scaffolds with random and aligned fiber orientations
in order to mimic the three-dimensional structure of the natural extracellular matrix (ECM)…

Cancer stem cells (CSCs) are hypothesized as tumor-initiating cells within tumors and main
contributors of tumor growth, metastasis and recurrence. Mammary cancer cells, MCF-7 cells…

Despite its importance as the leading cause of vascular dementia, the primary pathogenic
mechanisms in subcortical ischemic vascular dementia (SIVD) have remained elusive. …