Omega-3 fatty acids (ω-3 FAs) are essential fatty acids with diverse biological effects in
human health and disease. Reduced cardiovascular morbidity and mortality is a well-established …

A principal challenge currently facing biologists is how to connect the complete DNA sequence
of an organism to its development and behaviour. Large-scale targeted-deletions have …

Ageing is a fundamental, unsolved mystery in biology. DAF-16, a FOXO-family transcription
factor, influences the rate of ageing of Caenorhabditis elegans in response to insulin/insulin-…

Complete genomic sequence is known for two multicellular eukaryotes, the nematode
Caenorhabditis elegans and the fruit fly Drosophila melanogaster , and it will soon be known for …

The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a
common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. …

In Caenorhabditis elegans, introduction of double-stranded RNA (dsRNA) results in the
specific inactivation of an endogenous gene with corresponding sequence; this technique is …

Cheese Analogue (CA) is the term that can be described as a cheese-like-product produced
from the partial or complete substitution of components such as milk, milk fat, or milk protein …

Regulation of body fat storage involves signalling between centres that regulate feeding in
the brain and sites of fat storage and use in the body 1 , 2 . Here we describe an assay for …

We report a systematic RNA interference (RNAi) screen of 5,690 Caenorhabditis elegans
genes for gene inactivations that increase lifespan. We found that genes important for …

To explore the role of mitochondrial activity in the aging process, we have lowered the activity
of the electron transport chain and adenosine 5′-triphosphate (ATP) synthase with RNA …