With the gradual demographic shift toward an aging and obese society, an increasing number
of patients are suffering from bone and cartilage injuries. However, conventional therapies …

As chondrocytes from osteoarthritic cartilage usually exhibit aging and senescent characteristics,
targeting aging chondrocytes could be a potential therapeutic strategy. In this study, …

Melatonin is a multifunctional molecule that has been widely discovered in most plants. An
increasing number of studies have shown that melatonin plays essential roles in plant growth …

Liver tissue engineering (LTE) requires a perfect extracellular matrix (ECM) for hepatocytes
culture to maintain high level of liver-specific functions. Here, we reported a LTE scaffold …

Over the past decades, numerous tissue-engineered constructs have been investigated for
the osteochondral repair. However, it still remains a challenge to regenerate the …

Background Injury to articular cartilage cause certain degree of disability due to poor self-repair
ability of cartilage tissue. To promote cartilage regeneration, it is essential to develop a …

As emerging therapeutic factors, extracellular vesicles (EVs) offer significant potential for
myocardial infarction (MI) treatment. Current delivery approaches for EVs involve either intra‐…

Hydrogels, which provide three-dimensional (3D) niches for encapsulating bone marrow
mesenchymal stem cells (BMSCs), are becoming a promising tissue engineering solution for …

Bionic titanium bone tissue engineering implants were constructed by computer-aided design
and fabricated by selected laser melting. Novel interconnected porous structure was built …

Articular cartilage has very poor intrinsic healing ability and its repair remains a significant
clinical challenge. To promote neocartilage regeneration, we fabricated two collagen (Col) …