[HTML][HTML] A HapMap harvest of insights into the genetics of common disease

TA Manolio, LD Brooks… - The Journal of clinical …, 2008 - Am Soc Clin Investig
… Currently, genome-wide scans cost less than $1,000 per sample and include about 1 million
SNPs, with more SNPs in regions with low LD than in regions with high LD. As genotyping …

The international HapMap project

…, T Fujita, S Tanaka, AL Holden, FS Collins, LD Brooks… - 2003 - deepblue.lib.umich.edu
LD present in the genome. For common SNPs, which tend to be older than rare SNPs, the
patterns of LD … This explains the observations that haplotypes and patterns of LD are shared …

A DNA polymorphism discovery resource for research on human genetic variation

FS Collins, LD Brooks, A Chakravarti - Genome research, 1998 - genome.cshlp.org
Identifying the genes conferring susceptibility or resistance to common human diseases should
become increasingly feasible with improved methods for finding DNA sequence variants …

[HTML][HTML] ClinGen—the clinical genome resource

HL Rehm, JS Berg, LD Brooks… - … England Journal of …, 2015 - Mass Medical Soc
ClinGen — The Clinical Genome Resource | NEJM Skip to main content NEJM Group Follow Us
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …

The January anomaly: Effects of low share price, transaction costs, and bid‐ask bias

RK Bhardwaj, LD Brooks - The Journal of Finance, 1992 - Wiley Online Library
The January effect is primarily a low‐share price effect and less so a market value effect. In
the recent 1977–1986 period, after‐transaction‐cost raw and excess January returns are …

Evolution of recombination in a constant environment

…, FB Christiansen, LD Brooks - Proceedings of the …, 1980 - National Acad Sciences
The theory of evolution at a selectively neutral locus that controls the recombination between
two major loci that are under selection is studied. If the major loci are at a stable equilibrium …

The information content of municipal bond rating changes: A note

RW Ingram, LD Brooks, RM Copeland - The Journal of Finance, 1983 - JSTOR
MUNICIPAL BOND RATING CHANGES have positive social value if they signal previously
unavailable information on changes in municipal financial soundness. Weinstein [11] has …

The complexities of genomic identifiability

LL Rodriguez, LD Brooks, JH Greenberg, ED Green - Science, 2013 - science.org
Sharing research data has long been fundamental to the advancement of science. In today's
scientific culture, making research data available broadly and efficiently via the internet has …

The international HapMap project

…, T Fujita, S Tanaka, AL Holden, FS Collins, LD Brooks… - Nature, 2003 - hub.hku.hk
The goal of the International HapMap Project is to determine the common patterns of DNA
sequence variation in the human genome and to make this information freely available in the …

Characterizing genetic variants for clinical action

…, C Din‐Lovinescu, JS Berg, LD Brooks… - American Journal of …, 2014 - Wiley Online Library
Genome‐wide association studies, DNA sequencing studies, and other genomic studies are
finding an increasing number of genetic variants associated with clinical phenotypes that …