Reprogramming of human somatic cells to pluripotency with defined factors
Pluripotency pertains to the cells of early embryos that can generate all of the tissues in the
organism. Embryonic stem cells are embryo-derived cell lines that retain pluripotency and …
organism. Embryonic stem cells are embryo-derived cell lines that retain pluripotency and …
Nitrogen limitation constrains sustainability of ecosystem response to CO2
Enhanced plant biomass accumulation in response to elevated atmospheric CO 2 concentration
could dampen the future rate of increase in CO 2 levels and associated climate warming…
could dampen the future rate of increase in CO 2 levels and associated climate warming…
Molecular paleohydrology: interpreting the hydrogen-isotopic composition of lipid biomarkers from photosynthesizing organisms
Hydrogen-isotopic abundances of lipid biomarkers are emerging as important proxies in the
study of ancient environments and ecosystems. A decade ago, pioneering studies made …
study of ancient environments and ecosystems. A decade ago, pioneering studies made …
[HTML][HTML] Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
The association of genes with the nuclear pore complex (NPC) and nuclear transport factors
has been implicated in transcriptional regulation. We therefore examined the association of …
has been implicated in transcriptional regulation. We therefore examined the association of …
[PDF][PDF] The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites
Mechanistic roles for many lncRNAs are poorly understood, in part because their direct
interactions with genomic loci and proteins are difficult to assess. Using a method to purify …
interactions with genomic loci and proteins are difficult to assess. Using a method to purify …
Stable isotopes as one of nature's ecological recorders
Analyses of the natural variation in stable isotopes of components of ecological systems have
provided new insights into how these systems function across paleoecological to modern …
provided new insights into how these systems function across paleoecological to modern …
[BOOK][B] Isoscapes: understanding movement, pattern, and process on Earth through isotope mapping
… Bottom center: A leaf water isoscape provided courtesy of Jason West (see Chapter 8, this
… It was in this context that two of the editors of this book (West and Bowen) were engaged in …
… It was in this context that two of the editors of this book (West and Bowen) were engaged in …
A role for Lin28 in primordial germ-cell development and germ-cell malignancy
JA West, SR Viswanathan, A Yabuuchi, K Cunniff… - Nature, 2009 - nature.com
The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse
embryo thwart efforts to investigate molecular mechanisms of germ-cell specification. stella (also …
embryo thwart efforts to investigate molecular mechanisms of germ-cell specification. stella (also …
The genomic binding sites of a noncoding RNA
…, CI Wang, PV Kharchenko, JA West… - Proceedings of the …, 2011 - National Acad Sciences
Long noncoding RNAs (lncRNAs) have important regulatory roles and can function at the
level of chromatin. To determine where lncRNAs bind to chromatin, we developed capture …
level of chromatin. To determine where lncRNAs bind to chromatin, we developed capture …
Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization
Paraspeckles are nuclear bodies built on the long noncoding RNA Neat1, which regulates a
variety of physiological processes including cancer progression and corpus luteum …
variety of physiological processes including cancer progression and corpus luteum …