Shortly after being elbowed in the flank during a basketball game, a 35-year-old healthy man
has severe, colicky abdominal pain followed by gross hematuria. A renal ultrasound scan …

Coronary chronic total occlusions (CTOs) are frequently identified during coronary angiography
and remain the most challenging lesion group to treat. Patients with CTOs are frequently …

The American College of Cardiology, Society for Cardiovascular Angiography and Interventions,
Society of Thoracic Surgeons, and American Association for Thoracic Surgery, along …

Background The course of autosomal dominant polycystic kidney disease (ADPKD) is often
associated with pain, hypertension, and kidney failure. Preclinical studies indicated that …

Background Autosomal dominant polycystic kidney disease (ADPKD) is characterized by
progressive enlargement of cyst-filled kidneys. Methods In a three-year study, we measured …

METHODS Dissection. In the initial studies the kidneys were dissected following treatment
with collagenase. It was found that tubules pretreated with collagenase were not satisfactory …

The rate of renal disease progression varies widely among patients with autosomal dominant
polycystic kidney disease (ADPKD), necessitating optimal patient selection for enrollment …

Mutation-based molecular diagnostics of autosomal dominant polycystic kidney disease (ADPKD)
is complicated by genetic and allelic heterogeneity, large multi-exon genes, …

Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort …

Background Hypertension is common in autosomal dominant polycystic kidney disease (ADPKD)
and is associated with increased total kidney volume, activation of the renin–…