The in vitro splicing reactions of pre-messenger RNA (pre-mRNA) in a yeast extract were
analyzed by glycerol gradient centrifugation. Labeled pre-mRNA appears in a 40S peak only if …

Interrogation of the human proteome in a highly multiplexed and efficient manner remains a
coveted and challenging goal in biology. We present a new aptamer-based proteomic …

Aptamers are oligonucleotides derived from an in vitro evolution process called SELEX.
Aptamers have been evolved to bind proteins which are associated with a number of disease …

BACKGOUND:: Aptamers are single-stranded oligonucleotides derived from an in vitro
evolution protocol called systematic evolution of ligands by exponential enrichment (SELEX). …

The overall redox potential of a cell is primarily determined by oxidizable/reducible chemical
pairs, including glutathione–glutathione disulfide, reduced thioredoxin–oxidized thioredoxin…

The rexA and rexB genes of bacteriophage lambda encode a two-component system that
aborts lytic growth of bacterial viruses. Rex exclusion is characterized by termination of …

Escherichia coli rho-independent transcription terminators are characterized by an RNA
structure having a G + C-rich stem-loop followed by a series of uridine residues, but they can be …

Instrumentation has been developed to conduct Brillouin scattering measurements on small
(0.15 mm) transparent single crystals at hydrostatic pressures up to 35 kilobars in a …

In order to study the Salmonella typhimurium cobalamin biosynthetic pathway, the S.
typhimurium cob operon was isolated and cloned into Escherichia coli. This approach has given …

Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights into
disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs of …