User profiles for Babak Javid
Babak JavidUniversity of California, San Francisco Verified email at ucsf.edu Cited by 2628 |
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
B Javid, F Sorrentino, M Toosky… - Proceedings of the …, 2014 - National Acad Sciences
Errors are inherent in all biological systems. Errors in protein translation are particularly
frequent giving rise to a collection of protein quasi-species, the diversity of which will vary …
frequent giving rise to a collection of protein quasi-species, the diversity of which will vary …
[HTML][HTML] Antibodies and tuberculosis: finally coming of age?
Are antibodies important for protection against tuberculosis? The jury has been out for more
than 100 years. B cell depletion in experimental Mycobacterium tuberculosis infection failed …
than 100 years. B cell depletion in experimental Mycobacterium tuberculosis infection failed …
The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity
Although regulation of translation fidelity is an essential process 1–7, diverse organisms and
organelles have differing requirements of translational accuracy 8–15, and errors in gene …
organelles have differing requirements of translational accuracy 8–15, and errors in gene …
Selective translation by alternative bacterial ribosomes
Alternative ribosome subunit proteins are prevalent in the genomes of diverse bacterial
species, but their functional significance is controversial. Attempts to study microbial ribosomal …
species, but their functional significance is controversial. Attempts to study microbial ribosomal …
[HTML][HTML] The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis
…, A Bainomugisa, A Mandal, A Roohi, B Javid… - The Lancet …, 2022 - thelancet.com
Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex (MTBC…
Covid-19: should the public wear face masks?
B Javid, MP Weekes, NJ Matheson - Bmj, 2020 - bmj.com
When covid-19 became a global health emergency, there was a visible contrast between the
responses of citizens in east Asia and the rest of the world. In east Asia, wearing of masks …
responses of citizens in east Asia and the rest of the world. In east Asia, wearing of masks …
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212
…, S Alfonso, C Battilocchio, B Javid… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The 1,5-diarylpyrrole derivative BM212 was previously shown to be active against multidrug-resistant
clinical isolates and Mycobacterium tuberculosis residing within macrophages as …
clinical isolates and Mycobacterium tuberculosis residing within macrophages as …
Structure and function: heat shock proteins and adaptive immunity
Heat shock proteins (HSPs) have been implicated in the stimulation and generation of both
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …
Protein mistranslation: friend or foe?
The translation of genes into functional proteins involves error. Mistranslation is a known
cause of disease, but, surprisingly, recent studies suggest that certain organisms from all …
cause of disease, but, surprisingly, recent studies suggest that certain organisms from all …
Latently and uninfected healthcare workers exposed to TB make protective antibodies against Mycobacterium tuberculosis
The role of Igs in natural protection against infection by Mycobacterium tuberculosis (Mtb),
the causative agent of TB, is controversial. Although passive immunization with mAbs …
the causative agent of TB, is controversial. Although passive immunization with mAbs …